SHIMAMOTO LAB
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Organelle micromechanics at Japan's National Institute of Genetics

​We study the dynamics of cytoskeleton in vertebrate eggs and embryos, by using a combination of high-resolution imaging, biophysical nanomanipulation, cell biology and materials science. 
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NEWS (last update on Feb 25, 2025)
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2/18/25
Our previw article on embryonic spindle dynamics by Di Talia's group is out! 
Tanaka and Shimamoto, Curr Biol 2025


12/04/24
Our protocol on AI-based analysis of bipolar and multipolar spindle assembly in cell-free Xenopus egg extracts is out! Tanaka et al., Methods Mol Biol 2025

10/14/24
Our collaborative study with Kuo-Chiang Hsa's group at Academia Sinica is out!
Saju et al., Nat Commun 2024


10/4/24
Yuta gave a talk at the 52nd Naito Conference: Frontiers of Physical and Mechanical Biology.

https://confit.atlas.jp/guide/event/naito52/top?lang=ja

10/1/24
Amruta's review paper on spindle self-organization is out! Congrats!!
https://link.springer.com/article/10.1007/s12551-024-01236-z

10/1/24
Amruta joined the lab as a graduate student at SOKENDAI university. Warm welcome!

6/8/24
Yuta gave a talk at EMBO|EMBL symposium  Microtubules: from atoms to complex systems.
​https://www.embl.org/about/info/course-and-conference-office/events/ees24-07/​

4/1/24
Akihiro won the JSPS postdoctoral fellowship. Congrats! 

1/24/24
Our collaborative work with Satoshi Goto's lab at Rikkyo University is out!
Yamamoto-Hino et al., J Cell Biol, 2024
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11/14/23
Yuta gave a talk at the 61th Annual Meeting of Japan's Biophysical Society and organized a symposium titled "Cytoskeletal dynamics at boudaries." 

Masahito gave a poster presentation there.

11/13/23
Our collaborative work with Yoshihisa Oda's lab at Nagoya University is out!
​Sasaki et al., Nat Commun, 2023
Press release:
​https://www.nig.ac.jp/nig/ja/2023/11/research-highlights_ja/pr20231113.html
​

11/1/23
田中彬寛君が遺伝研のフェローシップを獲得し、遺伝研ポスドクとして研究を開始しました!

10/31/23
Yuta gave a talk at the 96th annual meeting of Japan's Physiological Society in Fukushima. 

7/27-28/23
Hata-san and Yuta organized the Cell Division Meeting in NIG campus.
https://www.nig.ac.jp/nig/ja/research/nig-meetings?id=1486


7/26/23
Lam Nyugen from Vietnam successfully completed his 6-week internship program in the lab. He worked on in vitro reconstitution of a mitotic kinesin and produced an exciting outcome. Great work!!

6/22/23
We headed to a campus-wide retreat in Gotenba:)

4/1/23
Akihiro Tanaka joined the lab. Welcome!!

4/1/23
Masahito Tanaka started his career as the JSPS postdoctoral fellow. Congratulations!

3/15/23
Yuta gave a talk at the 100th anniversary of the Physiology Society of Japan meeting in Kyoto.

1/19/23
Yuta gave a talk at Genome Stability Meeting  in University of Sussex.

1/6/23
Kei gave a talk at Seitai Undou Han Meeting in Tokyo. 

12/4/2022
Yuta gave a talk at ASCB/EMBO Cell Bio meeting in Washington D.C.

12/1/2022
Masahito gave a talk at Molecular Biology Society of Japan Annual Meeting in Makuhari. 

11/30/2022
Yuta gave a talk at the Molecular Biology Society of Japan Annual Meeting in Makuhari. Yuta also organized a workshop focusing on nucleoskeletal and cytoskeletal dynamics. 


10/25/2022
We published a research paper on mitotic spindle assembly (Fukuyama et al., PNAS, 2022)! This is a collaborative work with our colleagues, Yusuke Maeda, Kuo-Chiang Hsia, and Jeff Ti Labs. 

・Kudos Article "Memory form-like material property of the cell division machine​"
・Press release

10/1/2022
Masahito got a conpetitive postdoctoral fellowship from JSPS! Congratulations!!

9/28/2022
Yuta organized a symposium at the Biophysical Society of Japan Annual Meeting in Hakodate (Co-organizer: Motoshi Kaya, University of Tokyo). We thank all the speakers and the audience to join us:)

7/28/2022
We organized "cell division meeting" at National Institute of Genetics (co-host: Shoji Hata at Tokyo University).

7/10/2022
Yuta gave talks at World Congress of Biomechanics in Taiwan.

8/25/2021
A collaborative work with Ikawa Lab (Osaka Univ) was published in Journal of Cell Biology (Mori et al., J Cell Biol 2021)! The study focused on the mechanism demixing paternal chromosome from maternal chromosomes in a fertilized embryo of mouse. 

6/16/2021
Yuta gave a talk at the Biomechanical Engineering Society of Japan Annual Meeting (Zoom). 

4/1/2021
Kei Saito joined the lab! Welcome!! 

11/30/2020
We released a preprint of our work on mitotic spindle self-organization (Yan et al., arXiv 2020)!

11/2/2020
Yuta gave a talk at the Molecular Biology Society of Japan Annual Meeting (Zoom). 

9/18/2020
Yuta gave a talk at the Biophysical Society of Japan Annual Meeting (Zoom). 

12/22/2019
Yuta gave a talk at the 37th chromosome workshop in Japan.

12/7/2019
Yuta gave a talk at ASCB/EMBO Annual Meeting in Washington DC. Alex Dunn, Manu Prakash, and Sophie Dumont organized the session entitled "Mechanics of Large Cellular Machines." Thank you for the invitation!

10/1/2019
A new research assistant Naoko Watanabe joins our lab. Welcome!

4/22/2019
Jun's work on spindle micromechanics is published in Developmental Cell. Congratulations!!

9/18/2019
Yuta organized a symposium session at Biochemical Society of Japan Annual Meeting, with Daiju Kitagawa from University of Tokyo. Thank you to the speakers for their exciting talks.

3/31/2019
Yuta gave a talk at Circulation Society Annual Meeting in Yokohama.

11/24/2018
Yuta gave a talk at Motor protein meeting in Tokyo.

9/14/2018
Yuta gave a talk at Japan's Biophysical Society Annual Meeting in Okayama.

8/20/2018
Jun's work on spindle micromechanics is out in BioRxiv.

8/14/2018
Yuta gave a talk at the International Xenopus Conference in Seattle.
http://conferences.genetics-gsa.org/xenopus/2018/index​

4/1/2018
A new postdoc Gen Shiratsuchi joins our lab. Welcome!
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12/11/2017
Yuta gave a talk at UT Southwestern.

10/19/2017
Yuta gave a talk at the annual meeting of Japanese Society for Cell Synthesis Research in Kyoto.

6/13/2017
Yuta gave a talk at the annual meeting of Japanese Society for Cell Biology in Sendai.

5/31/2017
Jun's work on frozen Xenopus eg extract preparation is out in Molecular Biology of the Cell! Congratulations!!

4/5/2017
Our work on nuclear micromechanics is out in Molecular Biology of the Cell! Many thanks to Dr. Kazu Maeshima (NIG) and his lab members for this nice collaboration.

1/17/2017
Yuta gave a talk at the bioengineering society meeting in Nagoya.

12/4/2017
Yuta gave a microsymposium talk at the annual ASCB meeting in San Fransisco.

7/25/2016
Yuta gave a talk at Osaka University on collective force generation of mitotic motor proteins.

6/15/2016
Megumi Yamaoka joins our lab as a research assistant. Welcome!

1/12/2016
Yuta gave a talk at an international meeting of Japan Q-bio society.

11/7/2015
Yuta gave a public lecture at the annual NIG symposium in Tokyo.

9/29/2015
Jun & Yuta's review on spindle micromechanics is published in Journal of Biophysical Society of Japan.

9/28/2015
Yuta's work on collective force generation of mitotic motor protein kinesin-5 is published in Developmental Cell. 

8/15/2015
A Japanese textbook "Mechanobiology" is published. Yuta contributes to a section of the book.

4/15/2015
Yuta wins the Young Scientists' Prize from MEXT!

3/11/2015
Yuta gave a talk at National Institute for Physiological Sciences.

3/4/2015
Yuta gave a talk at Wako campus of RIKEN.

10/1/2014
Our first generation of Xenopus frogs has arrived through a long journey from Chiba prefecture. Welcome to the lab!

9/16/2014
A paper on in vitro reconstitution of the augmin complex is published in Nature Cell Biology. Yuta is one of the co-authors.

7/1/2014
Lab helper Mayumi Aono joins our lab. Welcome!
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7/1/2014
Postdoctoral fellow Jun Takagi joins our lab. Welcome!

7/1/2014
Official start of Shimamoto Lab at National Institute of Genetics.


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